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The exemestane resistance was investigated by Liu et al

About 30% to 40% of cases are labeled as idiopathic male infertility (IMI) which is diagnosed when there are normal findings on physical examination, and on genetic and hormonal evaluation, but semen analysis reveals abnormal parameters with failure to achieve fatherhood despite unprotected sexual intercourse [3]

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By contrast, the natural compound acteoside exerts a protective effect by downregulating ACSL4 (54)

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