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doi: 10.1016/J.CJCA.2025.03.011
In hyperinsulinemic ob/ob mice, P5 dosed at 1 g kg 1 only modestly potentiated the insulin secretory response when compared with control group, whereas Ex4 significantly increased the level of insulin when compared with either the control group or to the P5-treated group (Fig

Cross-trial comparison is inherently limited

The addition of basal insulin to metformin for dual therapy is considered the highest efficacy option according to the ADA Standards of Care

In addition, the treatment duration among patients taking two or more antidiabetic drugs was shorter than patients taking GLP-1 RAs, which possibly results in a low incidence of DR and a biased association
Formel: Gewicht (kg) / (Gre in m)