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As a result of this inflammation, the extraocular muscles become inflamed and swollen, leading to a range of symptoms, including proptosis or bulging of the eyes, double vision, and exposure keratopathy

Until that data becomes available, the Phase 2 results showing no thyroid safety signals, combined with the broader class experience, suggest the thyroid concern does not materially differ between GLP-1 medications

Disclosure Provenance and Peer Review: Not commissioned, externally peerreviewed

All three retatrutide groups had a greater reduction in apnea-hypopnea Index from baseline to 80 weeks compared with placebo

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Pharmacological characterization of ZYDPLA1, a novel long-acting dipeptidyl peptidase-4 inhibitor