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Its been an extraordinary week, said Prof Susan Jebb, a public health nutrition scientist at the University of Oxford, who has been researching obesity treatments since the 1980s and who presented the findings at the ECO meeting

"Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide." Cell Discovery 10.1 (2024): 77

Doses are raised in small steps over weeks so your gut has time to adjust, which is why rushing tends to backfire

Butler PC, Elashoff M, Elashoff R, et al

Cincinnati Childrens Hospital Clinical Research Center (UL1 TR000077)

Mounjaro may be a better fit when the primary diagnosis is type 2 diabetes and the goal is improved blood sugar control