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Pharmacological stabilization of HIF-1 has been shown to induce expression of the vitamin D receptor and antimicrobial peptide hBD-2, while simultaneously reducing the release of TNF- and IL-10, thereby significantly inhibiting bacterial proliferation (Nickel et al., 2012)

Male reproductive capacity may have declined due to other circumstances as well

Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage

Its effect begins after 24 weeks of continuous use, with progressive improvement up to 6 months [52]

J Clin Invest (2020) 130(3):1491505

Rab GTPases: master regulators that establish the secretory and endocytic pathways