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Patients (n = 9,340) were randomised to liraglutide or placebo for 3.5 and up to five years and showed durable effects on glycated haemoglobin and on body weight

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Oral semaglutide has proven to be noninferior to placebo in high-risk patients in a pre-approval study (30), and a larger trial to evaluate the long-term cardiovascular benefit of oral semaglutide is ongoing (NCT03914326)

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Eight cases with clinical and immunological characterization